E3 Ligase Ligand-linker Conjugate 169
E3 Ligase Ligand-linker Conjugate 169 is the conjugate composed of an E3 ligase ligand for Cereblon and a linker that can be used for synthesis of PROTAC degrader NU227326 (HY-173066) [1].
Product Specifications
UNSPSC
12352005
Target
E3 Ligase Ligand-Linker Conjugates
Related Pathways
PROTAC
Field of Research
Cancer
Smiles
O=C(CN1CCC(CC1)N2CCN(CC2)C3=CC=C4C(N(C5C(NC(CC5)=O)=O)C(C4=C3)=O)=O)O
Molecular Formula
C24H29N5O6
Molecular Weight
483.52
References & Citations
[1]Monsen PJ, et al., Rational Design and Optimization of a Potent IDO1 Proteolysis Targeting Chimera (PROTAC) . J Med Chem. 2025 Feb 27;68 (4) :4961-4987.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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