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E3 Ligase Ligand-linker Conjugate 169

E3 Ligase Ligand-linker Conjugate 169 is the conjugate composed of an E3 ligase ligand for Cereblon and a linker that can be used for synthesis of PROTAC degrader NU227326 (HY-173066) [1].

Product Specifications

UNSPSC

12352005

Target

E3 Ligase Ligand-Linker Conjugates

Related Pathways

PROTAC

Field of Research

Cancer

Smiles

O=C(CN1CCC(CC1)N2CCN(CC2)C3=CC=C4C(N(C5C(NC(CC5)=O)=O)C(C4=C3)=O)=O)O

Molecular Formula

C24H29N5O6

Molecular Weight

483.52

References & Citations

[1]Monsen PJ, et al., Rational Design and Optimization of a Potent IDO1 Proteolysis Targeting Chimera (PROTAC) . J Med Chem. 2025 Feb 27;68 (4) :4961-4987.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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