IDO1 ligand-1
IDO1 ligand-1 is the target protein ligand of PROTAC NU227326 (HY-173066) . NU227326 can be used to degrade IDO1[1].
Product Specifications
CAS Number
[3048196-74-0]
UNSPSC
12352005
Target
Indoleamine 2,3-Dioxygenase (IDO) ; Ligands for Target Protein for PROTAC
Related Pathways
Metabolic Enzyme/Protease; PROTAC
Field of Research
Others
Smiles
O=C(NC1=CC=CC(OC2CCNCC2)=C1)[C@H](C)[C@@]3([H])CC[C@](C4=C5C(C=CC(F)=C5)=NC=C4)([H])CC3
Molecular Formula
C29H34FN3O2
Molecular Weight
475.60
References & Citations
[1]Monsen PJ, et al. Rational Design and Optimization of a Potent IDO1 Proteolysis Targeting Chimera (PROTAC) . J Med Chem. 2025 Feb 27;68 (4) :4961-4987.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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