Ruthenoleuton
Ruthenoleuton is a 5-lipoxygenase (5-LOX) inhibitor with an IC50 of 3.49 μM and a Ki of 0.80 μM. Ruthenoleuton has antioxidant activity and can be used in the research of inflammatory diseases[1].
Product Specifications
UNSPSC
12352100
Target
Lipoxygenase
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Inflammation/Immunology
Smiles
[][Ru][].CC(c1cccc1)N(O)C(N)=O.c2cccc2
Molecular Formula
C13H16N2O2Ru
Molecular Weight
333.35
References & Citations
[1]Navarrete E, et al. Development of Ferrocenyl and Ruthenocenyl Zileuton Analogs with Enhanced Bioactivity toward Human 5-Lipoxygenase: Innovation in Drugs for Inflammatory Diseases. Inorg Chem. 2025 Feb 24;64 (7) :3495-3505.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
5-LOX
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