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2N4R Tau/α-Syn against-1

2N4R Tau/α-Syn against-1 (Compound 4d) targets α-synuclein and tau protein, inhibits the fibrillation and oligomer formation of α-synuclein and tau proteins, exhibits disaggregation activity on Aβ fibers. 2N4R Tau/α-Syn against-1 can be used in research of Parkinson's disease and Alzheimer's disease[1].

Product Specifications

UNSPSC

12352005

Target

α-synuclein

Related Pathways

Neuronal Signaling

Applications

Neuroscience-Neurodegeneration

Field of Research

Neurological Disease

Smiles

OC1=C(O)C(O)=CC(N2C=C(C3=CC=C(NC=C4)C4=C3)N=N2)=C1

Molecular Formula

C16H12N4O3

Molecular Weight

308.29

References & Citations

[1]Elbatrawy AA, et al., Inspecting the Triazole Scaffold as Powerful Antifibril Agents against 2N4R Tau and α-Synuclein Aggregates. ACS Omega. 2025 Feb 12;10 (7) :6721-6734.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

α-synuclein Aggregation

Frequently Asked Questions

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