2N4R Tau/α-Syn against-1
2N4R Tau/α-Syn against-1 (Compound 4d) targets α-synuclein and tau protein, inhibits the fibrillation and oligomer formation of α-synuclein and tau proteins, exhibits disaggregation activity on Aβ fibers. 2N4R Tau/α-Syn against-1 can be used in research of Parkinson's disease and Alzheimer's disease[1].
Product Specifications
UNSPSC
12352005
Target
α-synuclein
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Smiles
OC1=C(O)C(O)=CC(N2C=C(C3=CC=C(NC=C4)C4=C3)N=N2)=C1
Molecular Formula
C16H12N4O3
Molecular Weight
308.29
References & Citations
[1]Elbatrawy AA, et al., Inspecting the Triazole Scaffold as Powerful Antifibril Agents against 2N4R Tau and α-Synuclein Aggregates. ACS Omega. 2025 Feb 12;10 (7) :6721-6734.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
α-synuclein Aggregation
Curated Selection
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