Arginase inhibitor 9

Arginase inhibitor 9 (Compound 12a) is an arginase inhibitor with IC50 values of 9 μM and 55 μM for bovine and human arginase I, respectively. Arginase inhibitor 9 exhibits antioxidant activity and can scavenge free radicals. Additionally, Arginase inhibitor 9 can effectively regulate the levels of collagen and procollagen, exerting an anti-fibrotic effect[1].

Product Specifications

UNSPSC

12352005

Target

Arginase

Related Pathways

Immunology/Inflammation; Metabolic Enzyme/Protease

Field of Research

Inflammation/Immunology

Smiles

S=C(NC1=CC=C(O)C(O)=C1)C2=CC=C(O)C(O)=C2

Molecular Formula

C13H11NO4S

Molecular Weight

277.30

References & Citations

[1]Marchisio L, et al. Synthesis and evaluation of piceatannol derivatives as novel arginase inhibitors with radical scavenging activity and their potential for collagen reduction in dermal fibroblasts. Eur J Med Chem. 2025 Apr 5;287:117376.