CypA ligand-2

12352005

Cyclophilin; Ligands for Target Protein for PROTAC

Immunology/Inflammation; PROTAC

Infection

O=C1N2N[C@@H](CCC2)C(O[C@H](C)C3=CC=C4C(C=C(C=C4)/C=C/CC(N[C@H](C(N[C@H]1CC#C)=O)CC5=CC=C([N+]([O-])=O)C=C5)=O)=N3)=O

C34H34N6O7

638.67

[1]Newton LS, et al. Macrocycle-based PROTACs selectively degrade cyclophilin A and inhibit HIV-1 and HCV. Nat Commun. 2025 Feb 10;16 (1) :1484.

Room temperature

Reference compound1

No Development Reported

Cyclophilin A