AuL1

AuL1 is an inhibitor of topoisomerase IIα (Top II) with DNA-intercalating properties. AuL1 is cytotoxic to tumor cells and can be used in the research of anticancer agents[1].

Product Specifications

UNSPSC

12352005

Target

Topoisomerase

Related Pathways

Cell Cycle/DNA Damage

Field of Research

Cancer

Smiles

CCCC[N+](CCCC)(CCCC)CCCC.[N]1(CCC2)=CC3=CC=C[N-]3[Au+3]14[N]2=CC5=CC=C[N-]45.[Cl-].[Cl-]

Molecular Formula

C29H50AuCl2N5

Molecular Weight

736.61

References & Citations

[1]Sookai S, et al. Cytotoxic pyrrole-based gold (III) chelates target human topoisomerase II as dual-mode inhibitors and interact with human serum albumin. Eur J Med Chem. 2025 Apr 5;287:117330.