5-HT2A receptor agonist-8

5-HT2A receptor agonist-8 (compound 8) is a potent 5-HT2A receptor agonist with an EC50 of 0.6784 nM. 5-HT2A receptor agonist-8 can be used in the study of depressive disorders and bipolar disorders[1].

Product Specifications

CAS Number

[2855122-44-8]

UNSPSC

12352005

Target

5-HT Receptor

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Smiles

[H][C@@]12CC3=CNC4=C3C(C1=C[C@H](CN2CC=C)C(N[C@@H](CC)C)=O)=CC=C4

Molecular Formula

C22H27N3O

Molecular Weight

349.47

References & Citations

[1]Sabnis RW. Novel Ergoline Compounds as 5-HT2A Agonists for Treating Mood Disorders Such as Depressive Disorders and Bipolar Disorders. ACS Med Chem Lett. 2024 Dec 20;16 (1) :32-33.