TAU-IN-4
TAU-IN-4 (compound I1.21) is a potent Tau aggregation inhibitor with a KD of 1.58 μM. TAU-IN-4 can be used in the study of Alzheimer’s disease[1].
Product Specifications
CAS Number
[2109305-45-3]
UNSPSC
12352005
Target
Tau Protein
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Smiles
CC1=NOC(C2CCN(C2)C(CNC(C3=CC=CC=C3)=O)=O)=N1
Molecular Formula
C16H18N4O3
Molecular Weight
314.34
References & Citations
[1]Santambrogio, A., et al. Design of Tau Aggregation Inhibitors Using Iterative Machine Learning and a Polymorph-Specific Brain-Seeded Fibril Amplification Assay. bioRxiv, 2025-03.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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