Mitochondrial-IN-1
Mitochondrial-IN (C458) is a potent mitochondrial complex I inhibitor. Mitochondrial-IN demonstrates high protection against Aβ toxicity, favorable pharmacokinetics, and minimal off-target effects[1].
Product Specifications
CAS Number
2001090-87-3
UNSPSC
12352211
Target
Mitochondrial Metabolism
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Inflammation/Immunology; Neurological Disease
Smiles
CC1=CC=CC(O[C@@H]2CCC[C@H](C(C)CNCC3=CC=NC=C3)C2)=C1
Molecular Formula
C22H30N2O
Molecular Weight
338.49
References & Citations
[1]Trushin S, et al. Therapeutic assessment of a novel mitochondrial complex I inhibitor in in vitro and in vivo models of Alzheimer's disease. bioRxiv [Preprint]. 2025 Mar 21:2025.02.12.637918.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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