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ARCher-142

ARCher-142 (compound S8) is a potent tankyrase inhibitor. ARCher-142 selectively binds to ARC4 with potency of 8 µM[1].

Product Specifications

UNSPSC

12352005

Target

PARP

Related Pathways

Cell Cycle/DNA Damage; Epigenetics

Field of Research

Cancer

Smiles

CCC(CCCN1C(C(O)=C(C1C2=CC=C(C=C2)O)C(C3=CC=C4OCCOC4=C3)=O)=O)CC

Molecular Formula

C27H31NO6

Molecular Weight

465.54

References & Citations

[1]Bosetti, C., et al. Discovery of Tankyrase scaffolding inhibitor specifically targeting the ARC4 peptide binding domain. bioRxiv, 2025-03.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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