ARCher-142
ARCher-142 (compound S8) is a potent tankyrase inhibitor. ARCher-142 selectively binds to ARC4 with potency of 8 µM[1].
Product Specifications
UNSPSC
12352005
Target
PARP
Related Pathways
Cell Cycle/DNA Damage; Epigenetics
Field of Research
Cancer
Smiles
CCC(CCCN1C(C(O)=C(C1C2=CC=C(C=C2)O)C(C3=CC=C4OCCOC4=C3)=O)=O)CC
Molecular Formula
C27H31NO6
Molecular Weight
465.54
References & Citations
[1]Bosetti, C., et al. Discovery of Tankyrase scaffolding inhibitor specifically targeting the ARC4 peptide binding domain. bioRxiv, 2025-03.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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