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SARS-CoV-2 Mpro-IN-44

SARS-CoV-2 Mpro-IN-44 (Compound 25) is a broad-spectrum coronavirus main protease (Mpro) inhibitor. SARS-CoV-2 Mpro-IN-44 has inhibitory activity against a variety of high-risk coronaviruses (including SARS-CoV-2 and PEDV, etc.) (IC50: [1].

Product Specifications

CAS Number

3020713-53-2

UNSPSC

12352100

Target

SARS-CoV; Virus Protease

Related Pathways

Anti-infection

Applications

COVID-19-anti-virus

Field of Research

Infection; Inflammation/Immunology

Smiles

N#CC1=CC=C(OC2=CC(F)=C(Cl)C=C2CN3C(N(CC4=CC=CNC4=O)C(N/C3=N\C5=CC6=CN(C)N=C6C=C5Cl)=O)=O)S1

Molecular Formula

C29H19Cl2FN8O4S

Molecular Weight

665.48

References & Citations

[1]Liu M, et al. Identification of broad-spectrum Mpro inhibitors: a focus on high-risk coronaviruses and conserved interactions. J Enzyme Inhib Med Chem. 2025 Dec;40 (1) :2503961.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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