E3 Ligase Ligand-linker Conjugate 188
E3 Ligase Ligand-linker Conjugate 188 is a E3 ligase ligand-linker conjugate, used for the synthesis of AZ'3137 (HY-162702) [1].
Product Specifications
CAS Number
[3040074-87-8]
UNSPSC
12352005
Target
E3 Ligase Ligand-Linker Conjugates
Related Pathways
PROTAC
Field of Research
Cancer
Smiles
COC1=CC(N2CCN(CC3CCNCC3)CC2)=CC4=C1C(N(C5CCC(NC5=O)=O)C4)=O
Molecular Formula
C24H33N5O4
Molecular Weight
455.55
References & Citations
[1]Bagal SK, et al. Discovery of a Series of Orally Bioavailable Androgen Receptor Degraders for the Treatment of Prostate Cancer. J Med Chem. 2024 Jul 25;67 (14) :11732-11750.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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