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E3 ligase Ligand 65

E3 ligase Ligand 65 is a ligand for E3 ligase, used for the synthesis of AZ'3137 (HY-162702) [1].

Product Specifications

CAS Number

[2417258-70-7]

UNSPSC

12352005

Target

Ligands for E3 Ligase

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Smiles

COC1=CC(O)=CC2=C1C(N(C3CCC(NC3=O)=O)C2)=O

Molecular Formula

C14H14N2O5

Molecular Weight

290.27

References & Citations

[1]Bagal SK, et al. Discovery of a Series of Orally Bioavailable Androgen Receptor Degraders for the Treatment of Prostate Cancer. J Med Chem. 2024 Jul 25;67 (14) :11732-11750.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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