CAXII-IN-2
CAXII-IN-2 (compound 3j) is a potent CAXII inhibitor. CAXII-IN-2 inhibits CA IX and CAXII with Ki of 27.4 and 4.0 nM, respectively[1].
Product Specifications
UNSPSC
12352211
Target
Carbonic Anhydrase
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Cancer
Smiles
O=C(NC1=CC=C(OP(CC=C2)(O)=O)C2=C1)C3=CC=C(F)C=C3
Molecular Formula
C16H13FNO4P
Molecular Weight
333.25
References & Citations
[1]Balašova A, et al. Unraveling the Potential of Amino-, Acylamino-, and Ureido-Substituted 3 H-1, 2-Benzoxaphosphepine 2-Oxides toward Nanomolar Inhibitors of Tumor-Associated Carbonic Anhydrases IX and XII[J]. ACS Medicinal Chemistry Letters, 2025.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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