GPR40 Activator 3
GPR40 Activator 3 (compound SC) is a potent GPR40 activator. GPR40 Activator 3 mitigates pulmonary fibrosis by inhibiting M2 macrophage polarization via the GPR40/PKD1/CD36 axis[1].
Product Specifications
CAS Number
[2980-31-6]
UNSPSC
12352005
Target
Free Fatty Acid Receptor
Related Pathways
GPCR/G Protein
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Smiles
O=C1C2=C(OC3=C1C(OC)=CC=C3)C=C(O)C=C2O
Molecular Formula
C14H10O5
Molecular Weight
258.23
References & Citations
[1]Wan HQ, et al. GPR40 activation alleviates pulmonary fibrosis by repressing M2 macrophage polarization through the PKD1/CD36/TGF-β1 pathway. Acta Pharmacol Sin. 2025 May 14.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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