TEAD-IN-20
TEAD-IN-20 is a TEAD inhibitor. The IC50 values of TEAD-IN-20 in TEAD4 FRET and TEAD4 MCF7-Tead cell lines are 0.021 and 0.044 μM, respectively. TEAD-IN-20 can be used in cancer research[1].
Product Specifications
CAS Number
[3007592-85-7]
UNSPSC
12352005
Target
YAP
Related Pathways
Stem Cell/Wnt
Field of Research
Cancer
Smiles
CN1C=NC2=C(C(N[C@@H]3COC[C@@H](C3)O)=NC=C2C4=CC=C(C=C4)C(F)(F)F)C1=O
Molecular Formula
C20H19F3N4O3
Molecular Weight
420.39
References & Citations
[1]Wu Dedong, et al. Crystalline forms of tead inhibitor. WO2025088571A1. Astrazeneca Ab. 2024-10-25
Shipping Conditions
Room temperature
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-172932/
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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