Antidiabetic agent 15

Antidiabetic agent 15 (compound 1B15) is a AT1R and NEP dual inhibitor. Antidiabetic agent 15 reduces the oxidative stress and restores the mitochondrial membrane potential[1].

Product Specifications

UNSPSC

12352211

Target

Angiotensin Receptor; Neprilysin

Related Pathways

GPCR/G Protein; Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease; Neurological Disease; Cardiovascular Disease

Smiles

O=C(C1=C(NC(C2=CC=CC(C)=C2)=O)OC3=C(C=CC(O)=C3)C1C4=CC=CC=C4)OCC

Molecular Formula

C26H23NO5

Molecular Weight

429.46

References & Citations

[1]Thakur S, et al. Design and development of chromene-3-carboxylate derivatives as antidiabetic agents: Exploring the antidiabetic potential via dual inhibition of angiotensin II type 1 receptor and neprilysin enzyme. Eur J Med Chem. 2025 May 6;293:117705.