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AKT-IN-27

AKT-IN-27 (4a) is a potential anticancer agent through selective therapeutic targeting of Akt-driven pathways. AKT-IN-27 (4a) induces apoptosis via caspase-3 activation, G2/M cell cycle arrest, and mitochondrial membrane potential disruption. AKT-IN-27 (4a) can be used in the research for TNBC (triple-negative breast cancer) [1].

Product Specifications

UNSPSC

12352211

Target

Akt; Apoptosis

Related Pathways

Apoptosis; PI3K/Akt/mTOR

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Smiles

O=C(C1=C(NC2=CC=CC=C2)SC(C3=O)=C1C(C4=C3C=CC=C4)=O)OCC

Molecular Formula

C21H15NO4S

Molecular Weight

377.41

References & Citations

[1]Soumen K. Manik, et al., Design, synthesis, and in vitro and in vivo biological evaluation of 2-amino-naphtho[2,3-b]thiophene-4,9-dione derivatives as potent anticancer agents. European Journal of Medicinal Chemistry. 8 May 2025.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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