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TRPA1-IN-4

TRPA1-IN-4 (12) is a TRPA1 inhibitor, with an IC50 of 45 nM. TRPA1-IN-4 (12) can be used in the pain research[1].

Product Specifications

UNSPSC

12352101

Target

TRP Channel

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Smiles

O=C([C@H]1N(S(=O)(C2=CC=C(F)C=C2)=O)CCC1)NCC3=NOC(C4=CC=C(C(F)(F)F)C=C4)=C3

Molecular Formula

C22H19F4N3O4S

Molecular Weight

497.46

References & Citations

[1]Valentina Albanese, et al. Identification of isoxazole-based TRPA1 inhibitors with analgesic effects in vivo. Eur J Med Chem. 2025 May 9:294:117732.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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