Apoptosis inducer 37
Apoptosis inducer 37 (Derivative 10) is an apoptosis inducer. Apoptosis inducer 37 exerts anticancer effects by inducing S-G2/M cell cycle arrest and promoting cell apoptosis. Apoptosis inducer 37 has significant inhibitory activity against HCT116, SKOV3 and HepG2 cancer cells (IC50 values are 24.98 μM, 26.15 μM and 23.09 μM, respectively) . Apoptosis inducer 37 has antitumor effects and can be used in ovarian cancer research[1].
Product Specifications
UNSPSC
12352211
Target
Apoptosis
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Smiles
[H][C@]12CC[C@@]34CC/C([C@@](CC[C@]3([C@@]1(CCC[C@@]2(C(O)=O)C)C)[H])(C4)C)=N\NS(=O)(C5=CC=C(C=C5)Br)=O
Molecular Formula
C27H37BrN2O4S
Molecular Weight
565.56
References & Citations
[1]Ding Y, et al. Synthesis of Isosteviol derivatives as potential anticancer agents, especially for ovarian Cancer: In vitro cytotoxicity, cell cycle arrest, network pharmacology and molecular docking study. Bioorg Med Chem Lett. 2025 Apr 29;124:130261.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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