(±) 7 (8) -DiHDTE
(±) 7 (8) -DiHDTE is a metabolite of Docosapentaenoic acid (22n-3). Docosapentaenoic acid (22n-3) is a component of phospholipids. Docosapentaenoic acid 22n-3 has inhibitory activity against α-amylase and α-glucosidase with IC50s of 17 and 22 μg/mL, respectively. Docosapentaenoic acid 22n-3 increases cell vitality. Docosapentaenoic acid 22n-3 has a weak anti-inflammatory effect[1][2][3].
Product Specifications
UNSPSC
12352211
Target
Amylases; Drug Metabolite; Glycosidase
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Inflammation/Immunology; Metabolic Disease
Smiles
CC/C=C\C/C=C\C/C=C\C/C=C\C[C@@H](O)[C@@H](O)CCCCCC(O)=O
Molecular Formula
C22H36O4
Molecular Weight
364.52
References & Citations
[1]Sinclair HM, et al. Essential fatty acids in perspective. Hum Nutr Clin Nutr. 1984 Jul;38 (4) :245-60.|[2]Peng H, et al. Cartilaginous Metabolomics Reveals the Biochemical-Niche Fate Control of Bone Marrow-Derived Stem Cells. Cells. 2022 Sep 21;11 (19) :2951.|[3]Sivaramakrishnan R, et al. In vitro anti-diabetic and anti-inflammatory activities of metabolites isolated from Marine Sponge, Heteronema erecta (Keller, 1889) and its in silico studies[J]. Research Journal of Biotechnology Vol, 2020, 15: 12.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Glucosidase
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