(±) 7 (8) -DiHDTE

(±) 7 (8) -DiHDTE is a metabolite of Docosapentaenoic acid (22n-3) (HY-113159) . Docosapentaenoic acid (22n-3) is a component of phospholipids. Docosapentaenoic acid 22n-3 has inhibitory activity against α-amylase and α-glucosidase with IC50s of 17 and 22 μg/mL, respectively. Docosapentaenoic acid 22n-3 increases cell vitality. Docosapentaenoic acid 22n-3 has a weak anti-inflammatory effect[1][2][3].

Product Specifications

UNSPSC

12352211

Target

Amylases; Drug Metabolite; Glycosidase

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Inflammation/Immunology; Metabolic Disease

Smiles

CC/C=C\C/C=C\C/C=C\C/C=C\C[C@@H](O)[C@@H](O)CCCCCC(O)=O

Molecular Formula

C22H36O4

Molecular Weight

364.52

References & Citations

[1]Sinclair HM, et al. Essential fatty acids in perspective. Hum Nutr Clin Nutr. 1984 Jul;38 (4) :245-60.|[2]Peng H, et al. Cartilaginous Metabolomics Reveals the Biochemical-Niche Fate Control of Bone Marrow-Derived Stem Cells. Cells. 2022 Sep 21;11 (19) :2951.|[3]Sivaramakrishnan R, et al. In vitro anti-diabetic and anti-inflammatory activities of metabolites isolated from Marine Sponge, Heteronema erecta (Keller, 1889) and its in silico studies[J]. Research Journal of Biotechnology Vol, 2020, 15: 12.