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IDB-001

IDB-001 is an inhibitor of ribosome PTC that inhibits protein synthesis in a sequence-selective manner. IDB-001 inhibits HCC-1143 with a EC50 value of 0.84 μM. IDB-001 inhibits MYC-dependent cancer cell viability[1].

Product Specifications

CAS Number

3079913-81-5

UNSPSC

12352211

Target

DNA/RNA Synthesis

Related Pathways

Cell Cycle/DNA Damage

Applications

Cancer-programmed cell death

Field of Research

Cancer

Concentration

10mM

Purity

99.48

Solubility

DMSO : 50 mg/mL (ultrasonic)

Smiles

O=C(NCC[C@@H]1CCCN1)O[C@H]([C@H](CN2)O)[C@H]2CC3=CC=C(C=C3)OC

Molecular Formula

C19H29N3O4

Molecular Weight

363.45

References & Citations

[1]Paige D. Diamond, et al. Context-dependent translation inhibition as a novel oncology therapeutic modality. bioRxiv. January 09, 2025.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, protect from light, stored under nitrogen)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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