IDB-001
IDB-001 is an inhibitor of ribosome PTC that inhibits protein synthesis in a sequence-selective manner. IDB-001 inhibits HCC-1143 with a EC50 value of 0.84 μM. IDB-001 inhibits MYC-dependent cancer cell viability[1].
Product Specifications
CAS Number
[3079913-81-5]
UNSPSC
12352211
Target
DNA/RNA Synthesis
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Concentration
10mM
Purity
99.48
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
O=C(NCC[C@@H]1CCCN1)O[C@H]([C@H](CN2)O)[C@H]2CC3=CC=C(C=C3)OC
Molecular Formula
C19H29N3O4
Molecular Weight
363.45
References & Citations
[1]Paige D. Diamond, et al. Context-dependent translation inhibition as a novel oncology therapeutic modality. bioRxiv. January 09, 2025.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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