Succinate dehydrogenase-IN-8
Succinate dehydrogenase-IN-8 (compound i19) is a potent succinate dehydrogenase (SDH) inhibitor. Succinate dehydrogenase-IN-8, an indene amino acid derivative, demonstrates potent in vitro antifungal activity against Rhizoctonia solani (EC50=0.1843 mg/L), Botrytis cinerea (EC50=0.4829 mg/L), and Sclerotinia sclerotiorum (EC50=0.1349 mg/L) [1].
Product Specifications
CAS Number
3030753-68-2
UNSPSC
12352005
Target
Fungal; Succinate Dehydrogenase
Related Pathways
Anti-infection; Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Infection
Smiles
O=C(C1=CN(C)N=C1C(F)F)NC2(C(NNC3=CC=C(Cl)C(Cl)=C3)=O)CC4=C(C=CC=C4)C2
Molecular Formula
C22H19Cl2F2N5O2
Molecular Weight
494.32
References & Citations
[1]Letian Zhang, et al. Design, Synthesis, and Bioactivity Evaluation of Novel Indene Amino Acid Derivatives as Succinate Dehydrogenase Inhibitors. J Agric Food Chem. 2025 Apr 30;73 (17) :10130-10143.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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