TrkA-IN-10
TrkA-IN-10 (PI-15R) is a TrkA inhibitor with the IC50 values of 17 nM, 8 nM, and 5 nM for TrkA, TrkB and TrkC, respectively. TrkA-IN-10 can be used in cancer research[1].
Product Specifications
UNSPSC
12352211
Target
Trk Receptor
Related Pathways
Neuronal Signaling; Protein Tyrosine Kinase/RTK
Field of Research
Cancer
Smiles
C[C@H](C1=CC=CC=C1)NC2=NC(C3=CC(NC(C)=O)=CC=C3)=CN=C2N
Molecular Formula
C20H21N5O
Molecular Weight
347.41
References & Citations
[1]Iliev P, et al. Challenging the "Undruggable"─Targeting STAT3 but Identifying Potent TrkA-Targeted Inhibitors. J Med Chem. 2025 May 8;68 (9) :9501-9524.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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