DDR Inhibitor 2

DDR Inhibitor 2 (compound 5a) is a discoidin domain receptor (DDR) inhibitor with an IC50 of 0.125 μM. DDR Inhibitor 2 can be used for study of fibrotic diseases[1].

Product Specifications

UNSPSC

12352005

Target

Discoidin Domain Receptor

Related Pathways

Protein Tyrosine Kinase/RTK

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Smiles

CN1C=C2C3=NC(NC4=CN(CCCNCCOC5=CC=C2C=C5)N=C4)=NC=C31

Molecular Formula

C21H23N7O

Molecular Weight

389.45

References & Citations

[1]Carzaniga L, et al. Macrocyclization: Enhancing Drug-like Properties of Discoidin Domain Receptor Kinase Inhibitors. ACS Med Chem Lett. 2025 Apr 7;16 (5) :784-789.