Antibacterial agent 276
Antibacterial agent 276 (compound B3) is an antibacterial agent with EC50 values of 1.32 μg/mL and 2.80 μg/mL against Xanthomonas oryzae pv.oryzae and Xanthomonas axonopodis pv.citri, respectively. Antibacterial agent 276 disrupts the intracellular redox balance, and results in the accumulation of reactive oxygen species (ROS) and subsequent induction of apoptosis[1].
Product Specifications
UNSPSC
12352005
Target
Apoptosis; Bacterial; Reactive Oxygen Species (ROS)
Related Pathways
Anti-infection; Apoptosis; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB
Applications
COVID-19-immunoregulation
Field of Research
Infection
Smiles
O=C(CCNCC1=CC=C(Cl)C=C1)N(CC2)C(C3=CC=C(OC(F)(F)F)C=C3)C4=C2C5=CC=CC=C5N4
Molecular Formula
C28H25ClF3N3O2
Molecular Weight
527.97
References & Citations
[1]Yang Y, et al. Discovery of new 1,2,3,4-tetrahydro-β-carboline derivatives decorated with 3-N-substituted propionyl moiety flexibly bridged-chain as reactive oxygen species inducer for efficient antibacterial treatment. Bioorg Chem. 2025 Jun 15;160:108473.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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