HDAC6-IN-56
HDAC6-IN-56 (compound 18d) is an inhibitor of HDAC6 with an IC50 of 1.3 nM. HDAC6-IN-56 suppresses S phase and induces apoptosis in HCT-116 colon cancer cells[1].
Product Specifications
UNSPSC
12352005
Target
HDAC
Related Pathways
Cell Cycle/DNA Damage; Epigenetics
Field of Research
Cancer
Smiles
ClC(SC=C1)=C1[C@H]2C3=C(C(C=CC=C4)=C4N3)C[C@@H]5N2C(CN(CCCCCCC(NO)=O)C5=O)=O
Molecular Formula
C25H27ClN4O4S
Molecular Weight
515.02
References & Citations
[1]Noreen Hemid, et al. Unlocking the potential of novel tetrahydro-β-carboline-based HDAC6 inhibitors for colorectal cancer therapy: Design, synthesis and biological evaluation. Bioorg Chem. 2025 Jun 15:160:108454.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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