MTOR inhibitor-27
MTOR inhibitor-27 (Compound 7e) is a mammalian target of rapamycin (mTOR) inhibitor with an IC50 value of 5.47 μM. mTOR inhibitor-27 can induce tumor cell apoptosis and arrest the cell cycle in the S-phase, thereby inhibiting cancer cell growth. mTOR inhibitor-27 is promising for research of cancers, such as skin cancer[1].
Product Specifications
UNSPSC
12352211
Target
Apoptosis; mTOR
Related Pathways
Apoptosis; PI3K/Akt/mTOR
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Smiles
O=C(N/N=C/C1=CC=C(C)S1)C2COC3=CC=CC=C3O2
Molecular Formula
C15H14N2O3S
Molecular Weight
302.35
References & Citations
[1]Akbar S, et al. Design, synthesis, and evaluation of 1,4-benzodioxane-hydrazone derivatives as potential therapeutics for skin cancer: In silico, in vitro, and in vivo studies. Bioorg Chem. 2025 Apr 11;160:108449.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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