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Caspase-3-IN-3

Caspase-3-IN-3 (compound 7) is a caspase 3 inhibitor. Caspase-3-IN-3 increases cellular ATP levels, inhibits caspase-3 activity, decreases nitrite production, suppresses cytokine-induced apoptosis, and restores Glucose -stimulated insulin secretion[1].

Product Specifications

CAS Number

1984421-81-9

UNSPSC

12352005

Target

Apoptosis; Caspase

Related Pathways

Apoptosis

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease

Smiles

FC1=CC=C(N=C(C2=CC=C(O)C(O)=C2)N3)C3=C1

Molecular Formula

C13H9FN2O2

Molecular Weight

244.22

References & Citations

[1]Zawawi NK, et al. Benzimidazole derivatives protect against cytokine-induced apoptosis in pancreatic β-Cells. Bioorg Med Chem Lett. 2015 Oct 15;25 (20) :4672-6.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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