Caspase-3-IN-3
Caspase-3-IN-3 (compound 7) is a caspase 3 inhibitor. Caspase-3-IN-3 increases cellular ATP levels, inhibits caspase-3 activity, decreases nitrite production, suppresses cytokine-induced apoptosis, and restores Glucose (HY-B0389) -stimulated insulin secretion[1].
Product Specifications
CAS Number
[1984421-81-9]
UNSPSC
12352005
Target
Apoptosis; Caspase
Related Pathways
Apoptosis
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Smiles
FC1=CC=C(N=C(C2=CC=C(O)C(O)=C2)N3)C3=C1
Molecular Formula
C13H9FN2O2
Molecular Weight
244.22
References & Citations
[1]Zawawi NK, et al. Benzimidazole derivatives protect against cytokine-induced apoptosis in pancreatic β-Cells. Bioorg Med Chem Lett. 2015 Oct 15;25 (20) :4672-6.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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