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Spirovirimat

Spirovirimat (Compound 7) is a potent Monkeypox virus (MPXV) p37 protein inhibitor with an IC50 value of 35 nM. Spirovirimat blocks the formation of extracellular virions by inhibiting viral membrane wrapping. Spirovirimat is promising for research of Monkeypox virus infections[1].

Product Specifications

CAS Number

[3051872-92-2]

UNSPSC

12352211

Target

Orthopoxvirus

Related Pathways

Anti-infection

Applications

COVID-19-anti-virus

Field of Research

Infection

Smiles

O=C(NN1C(CC2(CCCCC2)CC1=O)=O)C3=CC=C(C(F)(F)F)C=C3

Molecular Formula

C18H19F3N2O3

Molecular Weight

368.35

References & Citations

[1]Rossi S, et al. Discovery of p-Trifluoromethylbenzohydrazide Derivatives as Potent Antiviral Agents against Monkeypox Virus[J]. ACS Medicinal Chemistry Letters, 2025.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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