SCUT1-2

SCUT1-2 is a bifunctional antibacterial agent with good oral bioavailability in mice (F=56.8%) . SCUT1-2 can kill the vegetative cells of C. difficile with a MIC of 0.06-0.50 μg/mL, and inhibit spore germination in vitro. SCUT1-2 could alleviate the symptoms of weight loss and diarrhea in mice caused by C. difficile infection (CDI) and prevent recurrent CDI[1].

Product Specifications

CAS Number

2930140-57-9

UNSPSC

12352005

Target

Bacterial

Related Pathways

Anti-infection

Field of Research

Infection

Smiles

O[C@@H]1CC[C@@]2(C)[C@@](C[C@H](O)[C@]3([H])[C@]2([H])CC[C@@]4(C)[C@@]3([H])CC[C@@H]4[C@H](C)CCC(OCCN5C(C)=NC=C5[N+]([O-])=O)=O)([H])C1

Molecular Formula

C30H47N3O6

Molecular Weight

545.71

References & Citations

[1]Shi K, et, al. Metronidazole-ursodeoxycholic acid bifunctional antibacterial: A promising strategy to combat Clostridium difficile infection and prevent recurrence. Eur J Med Chem. 2025 Jul 5:291:117631.