EDMA (hydrochloride)
EDMA hydrochloride is a derivative of MDMA. EDMA hydrochloride is a substrate for multiple neurotransmitter transporters, including serotonin transporter (SERT), dopamine transporter (DAT), and norepinephrine transporter (NET) . EDMA hydrochloride has 5-HT releasing activity at SERT (EC50 = 117 nM) and MPP+ releasing activity at DAT (EC50 = 597 nM) and NET (EC50 = 325 nM) [1].
Product Specifications
CAS Number
2748304-41-6
UNSPSC
12352211
Target
5-HT Receptor; Dopamine Transporter; Drug Derivative; Serotonin Transporter
Related Pathways
GPCR/G Protein; Neuronal Signaling; Others
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Smiles
CC(CC1=CC2=C(C=C1)OCCO2)NC.Cl
Molecular Formula
C12H18ClNO2
Molecular Weight
243.73
References & Citations
[1]Del Bello F, et al. Ethylenedioxy homologs of N-methyl- (3,4-methylenedioxyphenyl) -2-aminopropane (MDMA) and its corresponding cathinone analog methylenedioxymethcathinone: Interactions with transporters for serotonin, dopamine, and norepinephrine. Bioorg Med Chem. 2015 Sep 1;23 (17) :5574-9.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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