S234984
S234984 (Compound 13) is a molecular glue enhancer can specifically bind to KBTBD4 and HDAC2 to form a stable ternary complex. S234984 can be used for anti-cancer study[1].
Product Specifications
UNSPSC
12352211
Target
HDAC
Related Pathways
Cell Cycle/DNA Damage; Epigenetics
Field of Research
Cancer
Purity
98.7200
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(OC)C1=CC2=C(C(C(NCCCN3CCCC3)=NC(CC4=CC=CC=C4)=N5)=C5N2)C=C1
Molecular Formula
C26H29N5O2
Molecular Weight
443.54
References & Citations
[1]Chen Z, et al. Structural mimicry of UM171 and neomorphic cancer mutants co-opts E3 ligase KBTBD4 for HDAC1/2 recruitment. Nat Commun. 2025 Apr 2;16 (1) :3144.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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