CIM-834
CIM-834 is an orally active and selective inhibitor targeting the coronavirus membrane protein (M protein), which potently blocks viral assembly against SARS-CoV-2 and SARS-CoV. CIM-834 binds to the short form of the M protein (Mshort) in a non-covalent manner, stabilizing Mshort and preventing its conformational switch to the long form (Mlong) required for virion assembly, thereby inhibiting viral particle formation. CIM-834 is promising for research of COVID-19 and other coronavirus infections[1].
Product Specifications
UNSPSC
12352005
Target
SARS-CoV; Virus Protease
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Purity
98.71
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CC1=NC(N2CCC(N(C)C3=CC(C(NCCN4CCCC4)=O)=CN=N3)CC2)=NC(C)=C1CC(C)C
Molecular Formula
C27H42N8O
Molecular Weight
494.68
References & Citations
[1]Laporte M, et al. A coronavirus assembly inhibitor that targets the viral membrane protein. Nature. 2025 Apr;640 (8058) :514-523.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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