α-Glucosidase-IN-88
α-Glucosidase-IN-88 (Compound 3K) is an orally active and potent α-glucosidase inhibitor with an IC50 value of 6.40 µM. α-Glucosidase-IN-88 inhibits carbohydrate hydrolysis by blocking the enzyme's ability to break down glycosidic bonds, thereby reducing postprandial blood glucose levels. α-Glucosidase-IN-88 is promising for research of type 2 diabetes mellitus (T2DM) [1].
Product Specifications
UNSPSC
12352211
Target
Glycosidase
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Metabolic Disease
Smiles
S=C(N/N=C/C1=COC2=C(C=CC(F)=C2)C1=O)NC3=CC=CC(Cl)=C3Cl
Molecular Formula
C17H10Cl2FN3O2S
Molecular Weight
410.25
References & Citations
[1]Noreen F, et al. Synthesis, in vitro, and in silico studies of 7-fluorochromone based thiosemicarbazones as α-glucosidase inhibitors. Sci Rep. 2025 Mar 21;15 (1) :9816.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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