Conglobatin B1

Conglobatin B1 is a compound that can be isolated from Australian Streptomyces MST-91080. Conglobatin B1 is cytotoxic to the NS-1 myeloma cell line with an IC50 of 0.084 μg/mL, but has low toxicity to NFF human fibroblasts. Conglobatin B1 can be used in the study of cancer[1].

Product Specifications

CAS Number

[3053775-15-5]

UNSPSC

12352005

Target

Others

Related Pathways

Others

Field of Research

Cancer

Smiles

C[C@@H](C[C@H](/C=C(C(O[C@H]([C@H](CC/C=C(C(O1)=O)\C)C)CC2=CN=CO2)=O)\C)C)[C@@H]1CC3=CN=CO3

Molecular Formula

C27H36N2O6

Molecular Weight

484.58

References & Citations

[1]Lacey HJ, et al. Conglobatins B-E: cytotoxic analogues of the C2-symmetric macrodiolide conglobatin. J Antibiot (Tokyo) . 2020 Nov;73 (11) :756-765.