E3 Ligase Ligand-linker Conjugate 176
E3 Ligase Ligand-linker Conjugate 176 is an E3 ligase ligand-linker conjugate. E3 Ligase Ligand-linker Conjugate 176 can be used to synthesize BMS-986458 (HY-172736) [1].
Product Specifications
CAS Number
[3005273-99-1]
UNSPSC
12352005
Target
E3 Ligase Ligand-Linker Conjugates
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Smiles
C[C@@H]1CNCC[C@H]1NC2=CC=C3C(N(N=C3C4CCC(NC4=O)=O)C)=C2
Molecular Formula
C19H25N5O2
Molecular Weight
355.43
References & Citations
[1]Lynda Groocock, et al. BMS-986458 a Potential First-in-Class, Highly Selective, Potent and Well Tolerated BCL6 Ligand Directed Degrader (LDD) Demonstrates Multi-Modal Anti-Tumor Efficacy for the Treatment of B-Cell Non-Hodgkin's Lymphoma. Blood. Volume 144, Supplement 1, 5 November 2024, Page 957.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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