E3 Ligase Ligand-linker Conjugate 176

E3 Ligase Ligand-linker Conjugate 176 is an E3 ligase ligand-linker conjugate. E3 Ligase Ligand-linker Conjugate 176 can be used to synthesize BMS-986458 (HY-172736) [1].

Product Specifications

CAS Number

[3005273-99-1]

UNSPSC

12352005

Target

E3 Ligase Ligand-Linker Conjugates

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Smiles

C[C@@H]1CNCC[C@H]1NC2=CC=C3C(N(N=C3C4CCC(NC4=O)=O)C)=C2

Molecular Formula

C19H25N5O2

Molecular Weight

355.43

References & Citations

[1]Lynda Groocock, et al. BMS-986458 a Potential First-in-Class, Highly Selective, Potent and Well Tolerated BCL6 Ligand Directed Degrader (LDD) Demonstrates Multi-Modal Anti-Tumor Efficacy for the Treatment of B-Cell Non-Hodgkin's Lymphoma. Blood. Volume 144, Supplement 1, 5 November 2024, Page 957.