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E3 Ligase Ligand-linker Conjugate 175

E3 Ligase Ligand-linker Conjugate 175 is an E3 ligase ligand-linker conjugate. E3 Ligase Ligand-linker Conjugate 175 can be used to synthesize PROTAC SMARCA2 degrader-33[2].

Product Specifications

UNSPSC

12352005

Target

E3 Ligase Ligand-Linker Conjugates

Related Pathways

PROTAC

Field of Research

Cancer

Smiles

CC1=C(SC=N1)C2=CC=C(C=C2)[C@@H](NC([C@@H]3C[C@H](CN3C([C@H](C(C)C)C4=CC(O[C@H](CN5CC[C@H](C5)O)C)=NO4)=O)O)=O)C

Molecular Formula

C32H43N5O6S

Molecular Weight

625.78

References & Citations

[1]Michael Hulse, et al. Abstract 3263: Preclinical characterization of PRT3789, a potent and selective SMARCA2 targeted degrader. June 2022Cancer Research 82 (12_Supplement) :3263-3263.|[2]Discovery of PRT3789, a first-in-human, highly potent and selective SMARCA2 targeted protein degrader.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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