FG-2101
FG-2101 is a selective and orally active non-hydroxamate LpxC inhibitor with an IC50 of ~1 nM. FG-2101 exhibits exquisite selectivity over other bacterial and human metalloenzymes. FG-2101 can be used for the study of Gram-negative bacteria infections including drug-resistant strains[1].
Product Specifications
CAS Number
2919723-66-1
UNSPSC
12352005
Target
Bacterial
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Smiles
N#CC1CN(C1)C[C@H](C2=CC=C(C=C2)C#CC3=CC=C(C=C3)CN4CCOCC4)CC5=C(C(NC=N5)=O)OP(O)(O)=O
Molecular Formula
C30H32N5O6P
Molecular Weight
589.58
References & Citations
[1]4185279-First disclosure of FG-2101: A novel non-hydroxamate inhibitor of LpxC for treating Gram-negative bacteria infections including drug-resistant strains.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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