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DSPE-PEG2000-RVG29

DSPE-PEG2000-RVG29 is a PEG compound which composed of DSPE and a Rabies virus glycoprotein 29 (RVG29) . RVG29 can bind specifically to the nicotinic acetylcholine receptor (nAChR) at the blood-brain barrier (BBB) and cross over the BBB[1].

Product Specifications

UNSPSC

12352200

Target

Liposome; nAChR

Related Pathways

Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease; Neuronal Signaling

Applications

Cancer-programmed cell death

Field of Research

Infection

Smiles

[Mal-Cys-YTIWMPENPRPGTPCDIFTNSRGKRASNG]C(CCOCCOC(NCCOP(OC[C@](COC(CCCCCCCCCCCCCCCCC)=O)([H])OC(CCCCCCCCCCCCCCCCC)=O)(O)=O)=O)=O.[n]

Molecular Weight

2000 (Average)

References & Citations

[1]Ji F, et al. Rabies virus glycoprotein 29 (RVG29) promotes CAR-T immunotherapy for glioma. Transl Res. 2023 Sep;259:1-12.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Biochemical Assay Reagents

Clinical Information

No Development Reported

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