PUC-55
PUC-55 is a 5-HT6R antagonist with a Ki of 37.5 nM that induces neuronal autophagy by inhibiting the mTOR pathway. It holds potential for research in the field of neurological disorders[1].
Product Specifications
UNSPSC
12352005
Target
5-HT Receptor
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Smiles
OC(C1=NN(S(=O)(C2=C3C=CC=CC3=CC=C2)=O)C4=C1C=CC=C4)CN5CCN(C6=CC=CC=C6OC)CC5
Molecular Formula
C30H30N4O4S
Molecular Weight
542.65
References & Citations
[1]Alcaíno JM, et al. Novel 5-HTR modulators as mTOR-dependent neuronal autophagy inductors. Sci Rep. 2025 Mar 11;15 (1) :8380.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
5-HT6 Receptor
Curated Selection
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