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DEL-I25

DEL-I25 is a potent GPX4 activator. DEL-I25 protects cells from ferroptosis[1].

Product Specifications

CAS Number

[3036889-54-7]

UNSPSC

12352005

Target

Glutathione Peroxidase

Related Pathways

Apoptosis; Metabolic Enzyme/Protease

Applications

Cancer-programmed cell death

Field of Research

Cancer

Smiles

O=C(N1CC(NC(CCC2=CC=C(N)C=N2)=O)C1)CN3C(C4=CC=CC=C4C3)=O

Molecular Formula

C21H23N5O3

Molecular Weight

393.44

References & Citations

[1]Liu H, et al. Selective Small-Molecule Activator of Patient-Derived GPX4 Variant. ACS Chem Biol. 2025 May 16;20 (5) :1107-1122.

Shipping Conditions

Room temperature

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-172675/

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

GPX4

Curated Selection

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