DEL-I25
DEL-I25 is a potent GPX4 activator. DEL-I25 protects cells from ferroptosis[1].
Product Specifications
CAS Number
[3036889-54-7]
UNSPSC
12352005
Target
Glutathione Peroxidase
Related Pathways
Apoptosis; Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Smiles
O=C(N1CC(NC(CCC2=CC=C(N)C=N2)=O)C1)CN3C(C4=CC=CC=C4C3)=O
Molecular Formula
C21H23N5O3
Molecular Weight
393.44
References & Citations
[1]Liu H, et al. Selective Small-Molecule Activator of Patient-Derived GPX4 Variant. ACS Chem Biol. 2025 May 16;20 (5) :1107-1122.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
GPX4
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