Trabectedin derivative 1 (TFA)
Trabectedin derivative 1 TFA is a selective DNA minor groove binder. Trabectedin derivative 1 TFA inhibits DNA transcription and repair to induce tumor cell apoptosis. Trabectedin derivative 1 TFA is promising for research of solid tumors such as soft tissue sarcoma and ovarian cancer[1].
Product Specifications
UNSPSC
12352211
Target
Apoptosis; DNA/RNA Synthesis
Related Pathways
Apoptosis; Cell Cycle/DNA Damage
Field of Research
Cancer
Purity
99.32
Solubility
DMSO : ≥ 100 mg/mL
Smiles
N#C[C@@H]([C@]1([H])CC2=CC(C)=C3OC)N([C@](CO4)([H])C5=C(OCO6)C6=C7C)[C@@]([C@@](N1C)([H])C2=C3O)([H])[C@@](SC[C@](C8=CC(OC)=C9N)(NCCC8=C9)C4=O)([H])C5=C7OC(C)=O.O=C(O)C(F)(F)F
Molecular Formula
C42H44F3N5O11S
Molecular Weight
883.89
References & Citations
[1]Bin Zou, et al. Anti-alpp/alppl2 antibodies, antibody-drug conjugates, and uses thereof. WO2025048716A1. 2025-03-06.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
bsm-52060R-BF680-01 20 µL
CK20 Recombinant Antibody, AbBy Fluor™ 680 Conjugated
Sign In for Pricing
View Details bsm-52060R-BF680-02 100 µL
CK20 Recombinant Antibody, AbBy Fluor™ 680 Conjugated
Sign In for Pricing
View Details 
