Resolvin D3 methyl ester
Resolvin D3 methyl ester is a methyl ester version of Resolvin D3 that may act as a lipophilic prodrug form which can alter its distribution and pharmacokinetic properties. Resolvin D3 is a potent immunoresolvent. Resolvin D3 can reduce neutrophil infiltration in vivo. Resolvin D3 can be produced in murine inflammatory exudates and human macrophages. Resolvin D3 can activate the human RvD1 and RvD5. Resolvin D3 is a potent enhancer of the uptake of apoptotic neutrophils by macrophages as well as a stimulator of IL-10[1].
Product Specifications
UNSPSC
12352211
Target
Endogenous Metabolite; Interleukin Related
Related Pathways
Immunology/Inflammation; Metabolic Enzyme/Protease
Field of Research
Inflammation/Immunology
Smiles
O[C@H](/C=C/C=C\C[C@H](/C=C/C=C/C=C\[C@H](CCC(OC)=O)O)O)C/C=C\CC
Molecular Formula
C23H34O5
Molecular Weight
390.51
References & Citations
[1]Dalli J, et al., Resolvin D3 and aspirin-triggered resolvin D3 are potent immunoresolvents. Chem Biol. 2013 Feb 21;20 (2) :188-201.
Shipping Conditions
Room temperature
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-172632/
Scientific Category
Natural Products
Clinical Information
No Development Reported
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