(R) -KRAS G12D inhibitor 28 (hydrochloride dihydrate)

(R) -KRAS G12D inhibitor 28 hydrochloride dehydrate is the hydrochloride dehydrate of (R) -KRAS G12D inhibitor 28 (HY-172626) . KRAS G12D inhibitor 28 (Compound 1) is a KRAS G12D inhibitor. KRAS G12D inhibitor 28 (Compound 1) can be used in the cancer research[1].

Product Specifications

CAS Number

[3081520-70-6]

UNSPSC

12352005

Target

Ras

Related Pathways

GPCR/G Protein; MAPK/ERK Pathway

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Smiles

ClC1=CC=C[C@@]([C@@]2=C(F)C(N=C(C)C3=C4N([C@H]5[C@H]6CN[C@@H]5C6)C([C@@H]7N(C(C8CC8)=O)[C@H]9[C@H](C9)C7)=C3)=C4C=C2CCC#N)=C1Cl.Cl.O.O

Molecular Formula

C35H37Cl3FN5O3

Molecular Weight

701.06

References & Citations

[1]Jiemin HU, et al. Crystalline forms of 3- (1- ((1 r,4r,5s) -2-azabicyclo[2.1.1 ]hexan-5-yl) -2- ((1 r,3r,5r) -2- (cyclopropanecarbonyl) -2-azabicyclo[3.1.0]hexan-3-yl) -7- (2,3-dichlorophenyl) -6-fluoro-4-methyl-1 h-pyrrolo[3,2-c]quinolin-8-yl) propanenitrile.